Hidden Xenoestrogens That Cause Fatigue, Low Mood & Weight Gain

How to avoid hormone-disrupting chemicals 

Discover where Hidden Xenoestrogens That Cause Fatigue, Low Mood & Weight Gain hide in cosmetics and household products.

What are xenoestrogens?

Xenoestrogens are a subtype of endocrine disruptors that specifically exhibit estrogen-like effects. They are in plastics, tap water, pesticides, birth control pills, cosmetics, and personal care products like shampoo, conditioner, body creams, and shower gels.

Estrogen is a crucial hormone for reproductive health, and the body regulates estrogen levels through a complex network of biochemical pathways. The chemical structure of xenoestrogens closely resembles that of natural estrogen.

Upon entering the body, xenoestrogens can elevate estrogen levels and bind to estrogen receptor sites like natural estrogen. This accumulation of estrogen can have profoundly detrimental effects, including links to breast, prostate, and testicular cancer, fertility problems, miscarriages, obesity, and diabetes.

Why are they bad?

Hormone disruptors, commonly referred to as endocrine disruptors (EDCs), are synthetic chemicals and compounds that impede the body's endocrine (hormone) system, causing adverse effects on the endocrine glands.

They disrupt the production, transport, metabolism, and excretion of natural hormones in the body, leading to various hormonal issues, including infertility, endometriosis, early puberty, and hormone-related cancers.

EDCs also have detrimental effects on growth and development, immune function, and the brain and nervous system.

Endocrine disruptors: where are they hiding?

Why do they cause 1) fatigue 2) low mood and 3) weight gain

While the direct mechanisms linking hormone disruptors to fatigue, low mood, and weight gain may not be universally established, some research suggests potential associations and indirect pathways. It's important to note that this field of study is complex, and individual responses can vary. Here are some insights into the possible connections:


  • Disrupted Endocrine Function: Hormone disruptors may interfere with the endocrine system, which regulates energy balance. Disruptions in hormonal signalling can lead to changes in metabolism and energy utilisation, potentially contributing to feelings of fatigue.
  • Thyroid Dysfunction: Some hormone disruptors, like polybrominated diphenyl ethers (PBDEs), have been linked to thyroid dysfunction. Since the thyroid plays a crucial role in energy metabolism, disruptions in thyroid function may result in fatigue.

Low Mood:

  • Impact on Neurotransmitters: Hormone disruptors may influence neurotransmitter levels in the brain, including serotonin and dopamine, which play key roles in mood regulation. Alterations in these neurotransmitters can contribute to feelings of low mood and even depression.
  • Inflammation: Some studies suggest that exposure to certain endocrine-disrupting chemicals may trigger inflammation in the body, including the brain. Chronic inflammation is associated with mood disorders and may contribute to a sense of low mood.

Weight Gain:

  • Metabolic Disruption: Hormone disruptors can interfere with metabolic processes, potentially leading to weight gain. For example, disruption of insulin signalling and glucose metabolism may contribute to the development of insulin resistance, a condition associated with weight gain.
  • Changes in Fat Storage: Certain endocrine disruptors, such as bisphenol A (BPA), have been linked to alterations in fat cell development and function. This could influence how the body stores and utilises fat, contributing to weight gain.
  • Endocrine Disruption: Hormone disruptors can affect hormones involved in appetite regulation, such as leptin and ghrelin. Changes in these hormones may lead to increased food intake and altered energy balance, contributing to weight gain.

It's crucial to acknowledge that research in this area is ongoing, and the exact mechanisms behind these associations may vary depending on the specific chemical, individual factors, and the duration and intensity of exposure. Additionally, other lifestyle factors such as diet, physical activity, and overall health can also contribute to these outcomes. 

Chemicals and toxins are all around us and at times are difficult to avoid. However, you do have total control over the foods you eat, the products you put on your skin and what you use to clean your house. Avoid harmful endocrine-disrupting chemicals and xenoestrogens by eating more organic, plant-based foods, drinking filtered water and using homemade skincare and cleaning products such as vinegar and water. Start reading the ingredient labels on food packaging and cosmetics, and steer clear of dairy, plastics and non-stick cookware. 

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